Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698803 | 0.88 | FOLH1 (0.58) | FOLH1TSHRSLC16A3ALDH1A1ADRB2 | |
| SCHEMBL20162476 | 0.87 | FOLH1 (0.61) | FOLH1TSHRSLC16A3ALDH1A1ADRB2 | |
| SCHEMBL31474045 | 0.87 | FOLH1 (0.70) | FOLH1TSHRSLC16A3CA1CA2 | |
| SCHEMBL23003 | 0.85 | TSHR (0.79) | FOLH1TSHRPTPN1CA1CA2 | |
| SCHEMBL11710027 | 0.84 | FOLH1 (0.61) | FOLH1TSHRSLC16A3ALDH1A1ADRB2 | |
| Ammonia Solution, Strong SCHEMBL27527756 | 0.83 | TSHR (0.76) | FOLH1TSHRPTPN1CA1CA2 | |
| SCHEMBL28370887 | 0.83 | TSHR (0.76) | FOLH1TSHRPTPN1CA1CA2 | |
| SCHEMBL729909 | 0.83 | FOLH1 (0.70) | FOLH1TSHRSLC16A3CA1CA2 | |
| SCHEMBL8702953 | 0.82 | FOLH1 (0.63) | FOLH1TSHRALDH1A1ADRB2 | |
| SCHEMBL9345842 | 0.81 | FOLH1 (0.68) | FOLH1TSHRSLC16A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834468-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANALGESICS TREATING RHEUMATIC DISEASE, BONE DISORDER, INJURIES | ZENECA LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |