Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12155266 | 0.92 | LTA4H (0.61) | LTA4HALDH1A1L3MBTL1MAPK1SLC15A1 | |
| SCHEMBL7740147 | 0.92 | LTA4H (0.61) | LTA4HALDH1A1L3MBTL1MAPK1SLC15A1 | |
| SCHEMBL7740145 | 0.92 | LTA4H (0.61) | LTA4HALDH1A1L3MBTL1MAPK1SLC15A1 | |
| Hydrochloric Acid SCHEMBL25286512 | 0.91 | LTA4H (0.60) | LTA4HALDH1A1L3MBTL1MAPK1SLC15A1 | |
| Hydrochloric Acid SCHEMBL3501117 | 0.91 | LTA4H (0.60) | LTA4HALDH1A1L3MBTL1MAPK1SLC15A1 | |
| Hydrochloric Acid SCHEMBL15387431 | 0.91 | LTA4H (0.60) | LTA4HALDH1A1L3MBTL1MAPK1SLC15A1 | |
| SCHEMBL30634632 | 0.88 | LTA4H (0.57) | LTA4HALDH1A1L3MBTL1SYKSLC7A5 | |
| SCHEMBL27475486 | 0.88 | LTA4H (0.57) | LTA4HALDH1A1L3MBTL1SYKSLC7A5 | |
| SCHEMBL30869171 | 0.88 | LTA4H (0.57) | LTA4HALDH1A1L3MBTL1SYKSLC7A5 | |
| SCHEMBL20943303 | 0.87 | ALDH1A1 (0.46) | LTA4HALDH1A1L3MBTL1MAPK1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |