Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699120 | 0.94 | PREP (0.39) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL8697435 | 0.85 | PTGS1 (0.48) | MAPTMEN1KMT2AL3MBTL1ATM | |
| SCHEMBL12134448 | 0.83 | LMNA (0.58) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL980653 | 0.81 | PREP (0.42) | KMT2APREPLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10469262 | 0.81 | PTGS2 (0.46) | PREPLMNATSHRCYP1A2 | |
| SCHEMBL5280416 | 0.79 | ELANE (0.57) | PREPALDH1A1ELANE | |
| SCHEMBL8644671 | 0.78 | PREP (0.37) | KMT2APREPLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8379284 | 0.78 | PREP (0.40) | MEN1KMT2APREPLMNAALDH1A1 | |
| SCHEMBL9700930 | 0.77 | PREP (0.40) | KMT2AL3MBTL1ATMPREPALDH1A1 | |
| SCHEMBL4604318 | 0.77 | MAPT (0.61) | MAPTPOLBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834506-A | TREATMENT OF HIV, AIDS; ANTIVIRAL ACTIVITY IMPROVED BY JUDICIOUS PLACEMENT OF POLAR SUBSTITUENTS | WARNER-LAMBERT COMPANY (US) | 1998-11-10 | — | — | US | disclosed |