Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699789 | 0.80 | ALDH1A1 (0.41) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8703169 | 0.79 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL8703660 | 0.78 | HSD11B1 (0.54) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL8699218 | 0.77 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL8699166 | 0.75 | HTR1D (0.57) | MEN1KMT2ATSHRLMNAMAPT | |
| SCHEMBL8705046 | 0.73 | RAB9A (0.38) | RAB9ASLC6A2SLC6A4SLC6A3ADRA2B | |
| SCHEMBL23760662 | 0.72 | ALDH1A1 (0.52) | ADRA2BADRA2CMEN1KMT2AALDH1A1 | |
| SCHEMBL8704859 | 0.72 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL8699195 | 0.72 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3ADRA2BADRA2C | |
| SCHEMBL15330612 | 0.72 | KMT2A (0.51) | HTR2AMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |