SCHEMBL8699218

SCHEMBL8699218

CC(Oc1ccc(Cl)cc1C=O)N(C)Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 4/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
SLC6A2 P23975 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRK1 P41145 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8706669 0.84 ALDH1A1 (0.44) MEN1KMT2ALMNASMN1; SMN2NPSR1
Hydrochloric Acid SCHEMBL8700184 0.83 ALDH1A1 (0.43) MEN1KMT2ASMN1; SMN2MAPT
SCHEMBL8699407 0.81 SLC6A4 (0.48) MEN1KMT2AGAASMN1; SMN2ADRA2B
Hydrochloric Acid SCHEMBL8704286 0.80 SLC6A4 (0.47) MEN1KMT2AGAASMN1; SMN2ADRA2B
SCHEMBL8699751 0.78 SLC6A2 (0.48) MEN1KMT2ALMNACYP1A2CYP3A4
SCHEMBL8393097 0.77 GAA (0.61) MEN1KMT2ALMNAGAASMN1; SMN2
Hydrochloric Acid SCHEMBL8699225 0.77 SLC6A2 (0.47) MEN1KMT2ALMNACYP1A2CYP3A4
SCHEMBL8699161 0.77 RAB9A (0.40) MEN1KMT2ALMNACYP1A2CYP2C9
SCHEMBL30933788 0.74 ERN1 (0.47) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL4209586 0.74 ERN1 (0.47) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736568-A ANTIALLERGENS; IMMUNOMODULANTS KNOLL AKTIENGESELLSCHAFT (DE) 1998-04-07 US disclosed