Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696598 | 0.74 | CHEK1 (0.38) | IKBKBHDAC1HDAC2ACLYMMP2 | |
| SCHEMBL8701679 | 0.71 | HDAC1 (0.57) | ALDH1A1SMN1; SMN2RECQLHDAC1HDAC2 | |
| SCHEMBL8696466 | 0.70 | CD274 (0.55) | MTNR1A | |
| SCHEMBL18094640 | 0.69 | PTGER3 (0.45) | IKBKBALDH1A1SMN1; SMN2RECQLRAB9A | |
| SCHEMBL8699070 | 0.67 | FFAR1 (0.49) | HDAC1HDAC2KDM4ELMNAMMP2 | |
| SCHEMBL3113545 | 0.67 | PTGER1 (0.44) | MTNR1A | |
| SCHEMBL18104526 | 0.66 | MGLL (0.50) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL11262500 | 0.66 | FFAR1 (0.63) | SMN1; SMN2HDAC1HDAC2NPC1RAB9A | |
| Biphenyl SCHEMBL27839781 | 0.65 | LTB4R (0.53) | SMN1; SMN2HDAC1HDAC2RAB9AHPGD | |
| SCHEMBL8698877 | 0.65 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HDAC1HDAC2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |