Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696572 | 0.81 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL8696466 | 0.78 | CD274 (0.55) | CD274PDCD1EPHX1 | |
| SCHEMBL8695760 | 0.75 | ALDH1A1 (0.43) | CD274PDCD1HDAC1 | |
| SCHEMBL25470419 | 0.74 | KCNA5 (0.51) | CD274PDCD1KCNA5HDAC1 | |
| SCHEMBL8700812 | 0.74 | S1PR1 (0.45) | CD274PDCD1 | |
| SCHEMBL31710569 | 0.73 | KCNA5 (0.50) | CD274PDCD1KCNA5HDAC1 | |
| SCHEMBL7710607 | 0.73 | KCNA5 (0.52) | CD274PDCD1EPHX1KCNA5HDAC1 | |
| SCHEMBL4699620 | 0.73 | BRD4 (0.52) | CD274PDCD1EPHX1KCNA5HDAC1 | |
| SCHEMBL8699284 | 0.72 | CA1 (0.45) | KCNA5HDAC1 | |
| SCHEMBL8699097 | 0.72 | CD274 (0.57) | CD274PDCD1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |