Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698539 | 0.77 | HDAC1 (0.59) | MEN1KMT2AALDH1A1CYP3A4MAPT | |
| SCHEMBL3124959 | 0.75 | ALDH1A1 (0.55) | CA2KCNA5MEN1KMT2AALDH1A1 | |
| SCHEMBL12050574 | 0.75 | KCNA5 (0.54) | KCNA5NAMPTALDH1A1HDAC1HDAC10 | |
| SCHEMBL3750932 | 0.75 | KCNA5 (0.54) | KCNA5HDAC1HTR7 | |
| SCHEMBL7791651 | 0.75 | KCNA5 (0.54) | CA1KCNA5NAMPTHDAC1HDAC10 | |
| SCHEMBL7862318 | 0.74 | KCNA5 (0.53) | CA1KCNA5NAMPTMAPTHDAC1 | |
| SCHEMBL8701223 | 0.74 | HDAC1 (0.62) | ALDH1A1SMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL27399235 | 0.73 | NQO2 (0.49) | CA1CA2NAMPTMEN1KMT2A | |
| SCHEMBL8698193 | 0.73 | KCNA5 (0.52) | CA1KCNA5NAMPTHDAC1HDAC10 | |
| SCHEMBL8699283 | 0.72 | CD274 (0.44) | KCNA5HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |