Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 14/20 | 0.55 |
| ▸ | HTR1A | P08908 | 13/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | HRH2 | P25021 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | HTR5A | P47898 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532401 | 0.86 | HTR1A (0.55) | HTR3AHTR1AADRB1HTR2ACYP1A2 | |
| SCHEMBL255197 | 0.81 | HTR3A (0.67) | HTR3AHTR1AADRB1HTR2ACYP1A2 | |
| SCHEMBL27536083 | 0.81 | ALDH1A1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL2534803 | 0.80 | HTR3A (0.68) | HTR3AHTR1AADRB1HTR2ACYP1A2 | |
| SCHEMBL233944 | 0.80 | HTR3A (0.61) | HTR3AHTR1AADRB1HTR2ACYP1A2 | |
| SCHEMBL13232531 | 0.79 | ALDH1A1 (0.54) | CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7830360 | 0.79 | KDR (0.50) | HTR3AHTR1AHTR2AHTR1BHTR2C | |
| SCHEMBL3920957 | 0.79 | HTR3A (0.55) | HTR3AHTR1AADRB1HTR2ACYP1A2 | |
| SCHEMBL13398441 | 0.79 | HTR3A (0.55) | HTR3AHTR1AADRB1HTR2ACYP1A2 | |
| SCHEMBL14686716 | 0.78 | HTR3A (0.51) | HTR3AHTR1AADRB1HTR2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128139-C | Novel piperazine derivative and process for producing the same | SAMJIN PHARM CO LTD (KR) | 2003-11-19 | — | — | CN | disclosed |
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| CN-1145620-A | New piperazine derivatives and its prepn. | SAMJIN PHARM CO LTD (KR) | 1997-03-19 | — | — | CN | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |