SCHEMBL255197

SCHEMBL255197

Cc1ccc(N2CCNCC2)c(C)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 13/20 0.67
HTR1A P08908 12/20 0.67
HTR3E A5X5Y0 1/20 0.65
HTR3B O95264 1/20 0.65
HTR3D Q70Z44 1/20 0.65
HTR3C Q8WXA8 1/20 0.65
ADRB1 P08588 6/20 0.61
HTR7 P34969 3/20 0.59
CYP1A2 P05177 2/20 0.59
ADRB2 P07550 2/20 0.59
CYP3A4 P08684 2/20 0.59
CYP2D6 P10635 2/20 0.59
CYP2C9 P11712 2/20 0.59
HRH2 P25021 2/20 0.59
HTR1B P28222 2/20 0.59
HTR2A P28223 2/20 0.59
HTR2C P28335 2/20 0.59
SLC6A4 P31645 2/20 0.59
HRH1 P35367 2/20 0.59
HTR5A P47898 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2534803 0.98 HTR3A (0.68) HTR3AHTR1AHTR3EHTR3BHTR3D
SCHEMBL7931333 0.93 HTR3A (0.61) HTR3AHTR1AHTR3EHTR3BHTR3D
Hydrochloric Acid SCHEMBL2366003 0.92 HTR3A (0.64) HTR3AHTR1AHTR3EHTR3BHTR3D
SCHEMBL255418 0.85 HTR1A (0.62) HTR3AHTR1AADRB1HTR7CYP1A2
SCHEMBL29805912 0.85 HTR1A (0.62) HTR3AHTR1AADRB1HTR7CYP1A2
SCHEMBL233944 0.83 HTR3A (0.61) HTR3AHTR1AHTR3EHTR3BHTR3D
Hydrochloric Acid SCHEMBL2959720 0.83 HTR1A (0.65) HTR3AHTR1AADRB1HTR7CYP1A2
SCHEMBL22839748 0.82 ALDH1A1 (0.60) HTR1AALDH1A1MAPTMCOLN3
SCHEMBL9832991 0.82 ALDH1A1 (0.65) ALDH1A1MAPTMCOLN3
SCHEMBL3920957 0.81 HTR3A (0.55) HTR3AHTR1AHTR3EHTR3BHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112831206-B Inorganic oxide dispersion with controllable water content and preparation method thereof 凯斯科技股份有限公司 2022-12-30 CN claimed
CN-104311519-B Functional food factor preparation and its application with mucosal lesion protective effect 山东理工大学 2018-12-18 CN claimed
US-10125226-B2 Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-11-13 US claimed
CN-104230915-B Phenylpiperazine derivatives containing thiazolidinedione and preparation method thereof and purposes 南京大学 2016-08-17 CN claimed
CN-104311519-A Preparation and application of functional food factor with gastric mucosal lesion protection effect UNIV SHANDONG TECHNOLOGY 2015-01-28 CN claimed
CN-104230915-A Thiazolidinedione-containing phenylpiperazine derivatives as well as preparation method and applications of thiazolidinedione-containing phenylpiperazine derivatives NANJING UNIVERSITY OF TECHNOLOGY 2014-12-24 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery UNIV JOHNS HOPKINS (US) 2026-04-02 US disclosed
US-12527746-B2 Peptide/particle delivery systems THE JOHNS HOPKINS UNIVERSITY (US) 2026-01-20 US disclosed
US-12503458-B2 5-hydroxytryptamine receptor 7 activity modulators and their method of use TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-12-23 US disclosed
EP-4642434-A2 LIPID COMPOSITIONS ON THE BASIS OF IONIZABLE LIPIDS, USE FOR DELIVERY TO IMMUNE CELLS Life Technologies Corporation (US) 2025-11-05 EP disclosed
US-12458700-B2 Amine-containing transfection reagents and methods for making and using same Life Technologies Corporation (US) 2025-11-04 US disclosed
WO-1996041802-A1 NOVEL HETEROAROMATIC PIPERAZINES FOR USE AS DRUGS PIERRE FABRE MEDICAMENT (FR) 1996-12-27 WO disclosed
WO-1996002525-A1 NOVEL ARYL PIPERAZINE-DERIVED PIPERAZIDE DERIVATIVES, METHODS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME PIERRE FABRE MEDICAMENT (FR) 1996-02-01 WO disclosed
EP-0114374-B1 SUBSTITUTED 4-AMINOMETHYLENE CHROMANS OR CHROMENES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES BAYER AG (DE) 1986-07-23 EP disclosed
US-4563458-A CIRCULATORY SYSTEM DISORDERS BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed
EP-0114374-A1 Substituted 4-aminomethylene chromans or chromenes, process for their preparation and their use in medicines BAYER AG (DE) 1984-08-01 EP disclosed
US-3983121-A 1-Substituted 4-(β-2-quinolylethyl)piperazines and 1,2,3,4-tetrahydroquinolyl-ethyl analogues thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503458-B2 5-hydroxytryptamine receptor 7 activity modulators and their method of use HTR7, HTR5A, HTR6 HTR3A 12/4885HTR1A 4/4885HTR3E 15/4885
US-12527746-B2 Peptide/particle delivery systems VEGFA, IGF2BP2, MSTN HTR3A 2147/4885HTR1A 1346/4885HTR3E 1396/4885
US-12458700-B2 Amine-containing transfection reagents and methods for making and using same SNRPA, NUDT21, SOAT2 HTR3A 2204/4885HTR1A 2495/4885HTR3E 2058/4885
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery SLC43A1, SLC7A5, SLC7A1 HTR3A 4257/4885HTR1A 4712/4885HTR3E 3569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.