Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143665 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL5857803 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9046912 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9313048 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9045211 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL10416126 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL10553544 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9546230 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9423301 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL5857804 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719275-A | REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC | SANKYO COMPANY, LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5681951-A | REACTING PENICILLIN DERIVATIVE HAVING SULFINYL OR SULFONYL GROUP IN 2 POSITION WITH SUBSTITUTED MERCAPTAN IN PRESENCE OF SALT OF GROUP IIA OR IIIA ELEMENT | SANKYO COMPANY, LIMITED (JP) | 1997-10-28 | — | — | US | disclosed |
| US-5075439-A | Processes for (3S,4R)-3-[1(R)-t-butyl-dimethylsilyloxy)-ethyl]-4-[1-oxo-3-thiolanylthio(thiocarbonyl)thio]azetidin-2-ones and intermediates therefor | PFIZER INC. (US) | 1991-12-24 | — | — | US | disclosed |
| US-4895939-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1990-01-23 | — | — | US | disclosed |
| US-4772683-A | SILYLATION, AZETIDONE THIOLESTERS | BRISTOL-MYERS COMPANY (US) | 1988-09-20 | — | — | US | disclosed |