Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143665 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL5857803 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9046912 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9313048 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL10416126 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL10553544 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9546230 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9423301 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL5857804 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL8699325 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548790-B1 | (1'S)-Hydroxyalkyloxapenem-3-carboxylic acids and their use as beta-lactamase inhibitors | LILLY CO ELI (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0171064-B1 | Azetidinone derivative and processes for production thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-07-12 | — | — | EP | disclosed |
| EP-0548790-A1 | (1'S)-Hydroxyalkyloxapenem-3-carboxylic acids and their use as beta-lactamase inhibitors | ELI LILLY AND COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| US-4845210-A | Azetidinone derivatives and processes for production thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0171064-A1 | Azetidinone derivative and processes for production thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |