Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143665 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL5857803 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9046912 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9313048 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9045211 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL10416126 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL10553544 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9546230 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL9423301 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL8699325 | 1.00 | CTSL (0.31) | CTSLCTSSCTSKCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197432-A2 | Enantioselective process for producing 1-beta-methylcarbapenem antibiotic intermediates | MERCK & CO. INC. (US) | 1986-10-15 | — | — | EP | claimed |
| JP-63222156-A | — | — | None | — | — | JP | disclosed |
| CN-112961156-A | Preparation process of antibiotic drug panipenem | 苏州莱克施德药业有限公司 | 2021-06-15 | — | — | CN | disclosed |
| WO-2008035153-A2 | PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |
| US-7115595-B2 | Carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20040063683-A1 | Novel carbapenem compounds | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-0974582-B1 | Process for the preparation of 4-substituted azetidinone derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6340751-B1 | REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0974582-A1 | Process for the preparation of 4-substituted azetidinone derivatives | Takasago International Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| EP-0171064-B1 | Azetidinone derivative and processes for production thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-07-12 | — | — | EP | disclosed |
| EP-0502464-A1 | Antibacterial condensed carbapenemes | GLAXO S.p.A. (IT) | 1992-09-09 | — | — | EP | disclosed |
| US-4960879-A | REACTING SUBSTITUTED AZETIDINONE WITH TRANS SUBSTITUTED-METHYL ALKYLACRYLIC ACID AND REDUCING METAL | SHIONOGI & CO., LTD. (JP) | 1990-10-02 | — | — | US | disclosed |
| US-4918184-A | REACTING 1,3-THIAZOLIDINE-2-THIONE DERIVATIVE WITH TIN TRIFLUOROMETHANESULFONATE TO FORM ENOLATE, REACTING WITH SUBSTITUTED AZETIDINONE | LEDERLE (JAPAN), LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0336143-A1 | A new process for carbapenem intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4845210-A | Azetidinone derivatives and processes for production thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| JP-S63222156-A | BETA-LACTAM INTERMEDIATE | KANEGAFUCHI CHEM IND CO LTD | 1988-09-16 | — | — | JP | disclosed |
| EP-0213610-A1 | Azetidin-2-one derivatives and process for production thereof | LEDERLE (JAPAN) LTD. (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4639441-A | ANTIBACTERIAL PENICILLINS | SANKYO COMPANY LIMITED (JP) | 1987-01-27 | — | — | US | disclosed |
| EP-0171064-A1 | Azetidinone derivative and processes for production thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063683-A1 | Novel carbapenem compounds | PTMS, PNISR, LRPPRC | CTSL 1528/4885CTSS 1570/4885CTSK 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.