Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699346 | 0.81 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1NPC1ALDH1A1 | |
| SCHEMBL8704202 | 0.81 | HDAC8 (0.47) | SLC1A3SLC1A2SLC1A1NPC1ALDH1A1 | |
| SCHEMBL15651195 | 0.75 | ALDH1A1 (0.51) | SLC1A3SLC1A2SLC1A1NPC1ALDH1A1 | |
| SCHEMBL8703814 | 0.74 | TERT (0.44) | SLC1A3SLC1A2SLC1A1TERT | |
| SCHEMBL8703823 | 0.74 | TERT (0.44) | SLC1A3SLC1A2SLC1A1TERT | |
| SCHEMBL8703139 | 0.73 | REN (0.50) | — | |
| SCHEMBL28597069 | 0.72 | SLC7A5 (0.76) | SLC1A3SLC1A2SLC1A1MAOACYP1A2 | |
| Anthraquinone SCHEMBL2033678 | 0.72 | TERT (0.55) | SLC1A3SLC1A2SLC1A1NPC1ALDH1A1 | |
| SCHEMBL30479701 | 0.72 | TERT (0.55) | SLC1A3SLC1A2SLC1A1NPC1ALDH1A1 | |
| SCHEMBL2814457 | 0.72 | MAOA (0.57) | SLC1A3SLC1A2SLC1A1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733880-A | ANTITUMOR AGENTS | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1998-03-31 | — | — | US | disclosed |