Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701270 | 0.79 | HPGD (0.54) | KMT2A | |
| SCHEMBL19844821 | 0.76 | KDM4E (0.54) | KDM4EKMT2ASIGMAR1 | |
| SCHEMBL19844793 | 0.76 | KDM4E (0.54) | KDM4EKMT2ASIGMAR1 | |
| SCHEMBL19844798 | 0.76 | KDM4E (0.54) | KDM4EKMT2ASIGMAR1 | |
| SCHEMBL8539478 | 0.73 | SLC6A2 (0.50) | KDM4EKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8539162 | 0.72 | SLC6A2 (0.49) | KDM4EKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8696472 | 0.72 | SIGMAR1 (0.44) | KMT2ASIGMAR1 | |
| SCHEMBL8699420 | 0.72 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8539669 | 0.70 | SIGMAR1 (0.47) | KMT2ASIGMAR1 | |
| SCHEMBL8698574 | 0.70 | CYP17A1 (0.41) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |