Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698745 | 0.77 | CYP24A1 (0.37) | CYP24A1 | |
| SCHEMBL8696473 | 0.74 | SIGMAR1 (0.46) | SIGMAR1MAPT | |
| SCHEMBL8698574 | 0.73 | CYP17A1 (0.41) | SIGMAR1 | |
| SCHEMBL11789646 | 0.73 | SIGMAR1 (0.62) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8698582 | 0.72 | CYP17A1 (0.41) | SIGMAR1 | |
| SCHEMBL8699418 | 0.72 | KDM4E (0.43) | SIGMAR1KMT2A | |
| SCHEMBL8695800 | 0.71 | SIGMAR1 (0.41) | SIGMAR1HRH3CYP24A1 | |
| SCHEMBL8698467 | 0.70 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL8545945 | 0.70 | HMOX1 (0.41) | SIGMAR1MAPT | |
| SCHEMBL726958 | 0.70 | SLC6A4 (0.55) | SIGMAR1MEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |