Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716519 | 0.81 | PSMB8 (0.59) | PSMB8ALDH1A1KDM4EGAAKEAP1 | |
| SCHEMBL8699552 | 0.73 | PSMB8 (0.68) | PSMB8ALDH1A1KDM4EGAAKEAP1 | |
| SCHEMBL8701782 | 0.73 | PSMB8 (0.68) | PSMB8ALDH1A1KDM4EGAAKEAP1 | |
| SCHEMBL8701312 | 0.72 | PSMB8 (0.62) | PSMB8ALDH1A1KDM4EGAAKEAP1 | |
| SCHEMBL8698949 | 0.71 | PKM (0.44) | ALDH1A1KDM4EGAAL3MBTL1HSD17B10 | |
| SCHEMBL8703483 | 0.69 | ALDH1A1 (0.52) | PSMB8ALDH1A1KDM4EGAAKEAP1 | |
| SCHEMBL15081590 | 0.69 | L3MBTL1 (0.58) | ALDH1A1KDM4EL3MBTL1MAPTHRH3 | |
| SCHEMBL8701154 | 0.68 | PSMB8 (0.43) | PSMB8ALDH1A1KDM4EGAAKEAP1 | |
| SCHEMBL8704890 | 0.68 | PSMB8 (0.53) | PSMB8ALDH1A1KDM4EGAAKEAP1 | |
| SCHEMBL31276017 | 0.67 | L3MBTL1 (0.66) | ALDH1A1L3MBTL1HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |