SCHEMBL138320

SCHEMBL138320

CC(=O)Oc1ccc(N)cc1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 2/20 0.69
KDM4E B2RXH2 9/20 0.58
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 4/20 0.58
TDP1 Q9NUW8 4/20 0.58
PTGS2 P35354 3/20 0.58
HPGD P15428 3/20 0.58
TSHR P16473 3/20 0.58
PTGS1 P23219 2/20 0.58
BLM P54132 2/20 0.58
ESR1 P03372 1/20 0.58
ITGB3 P05106 1/20 0.58
ITGA2B P08514 1/20 0.58
HMGB1 P09429 1/20 0.58
GGT1 P19440 1/20 0.58
NAPRT Q6XQN6 1/20 0.58
MAPT P10636 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
THRB P10828 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31618292 1.00 CFD (0.69) CFDKDM4EALDH1A1HSD17B10TDP1
Methoxymethane SCHEMBL5317565 0.97 CFD (0.65) CFDKDM4EALDH1A1HSD17B10TDP1
Aspirin SCHEMBL22972824 0.92 KDM4E (0.73) CFDKDM4EALDH1A1HSD17B10TDP1
SCHEMBL8699559 0.88 KDM4E (0.73) CFDKDM4EALDH1A1HSD17B10TDP1
SCHEMBL4737527 0.86 ALDH1A1 (0.69) CFDKDM4EALDH1A1HSD17B10TDP1
SCHEMBL3803677 0.85 ALDH1A1 (0.50) CFDKDM4EALDH1A1HSD17B10TDP1
SCHEMBL9318003 0.83 CFD (0.47) CFDKDM4EALDH1A1HSD17B10TDP1
SCHEMBL5317567 0.83 GAA (0.56) CFDKDM4EALDH1A1HSD17B10TDP1
SCHEMBL10764467 0.82 CFD (0.48) CFDKDM4EALDH1A1HSD17B10TDP1
Aspirin SCHEMBL2467028 0.82 KDM4E (0.67) CFDKDM4EALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210145763-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE EYE CO PTY LTD. (AU) 2021-05-20 US claimed
EP-3773651-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE Eye Co Pty Ltd. (AU) 2021-02-17 EP claimed
WO-2019191800-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE EYE CO PTY LTD (AU) 2019-10-10 WO claimed
US-8956647-B2 Pellet formulation for the treatment of the intestinal tract DR. FALK PHARMA GMBH (DE) 2015-02-17 US claimed
US-8911778-B2 Pellet formulation for the treatment of the intestinal tract DR. FALK PHARMA GMBH (DE) 2014-12-16 US claimed
US-8496965-B2 Pellet formulation for the treatment of the intenstinal tract DR. FALK PHARMA GMBH (DE) 2013-07-30 US claimed
US-20130177650-A1 PELLET FORMULATION FOR THE TREATMENT OF THE INTESTINAL TRACT DR. FALK PHARMA GMBH 2013-07-11 US claimed
US-20120308659-A1 PELLET FORMULATION FOR THE TREATMENT OF THE INTENSTINAL TRACT OTTERBECK NORBERT (DE) 2012-12-06 US claimed
WO-2005030224-A1 NITROSYLATED ANALGESIC AND/OR ANTI-INFLAMMATORY DRUGS HAVING ANTIVIRAL ACTIVITY NICOX S.A. (FR) 2005-04-07 WO claimed
US-20040072798-A1 Compositions comprising cyclodextrins and no-releasing drugs NICOX S.A. (FR) 2004-04-15 US claimed
EP-1347782-A1 COMPOSITIONS COMPRISING CYCLODEXTRINS AND NO-RELEASING DRUGS Nicox S.A. (FR) 2003-10-01 EP claimed
WO-2002053188-A1 COMPOSITIONS COMPRISING CYCLODEXTRINS AND NO-RELEASING DRUGS NICOX S.A. (FR) 2002-07-11 WO claimed
CN-1356981-A Pharmaceutical compounds NICOX SA (FR) 2002-07-03 CN claimed
EP-1219306-A1 Compositions comprising cyclodextrins and NO- releasing drugs NICOX S.A. (FR) 2002-07-03 EP claimed
EP-0504560-A1 Preparation of anhydride-capped polyphenylene ether in a melt process GENERAL ELECTRIC COMPANY (US) 1992-09-23 EP claimed
EP-0501154-A2 Polyphenylene ether-polyamide compositions GENERAL ELECTRIC COMPANY (US) 1992-09-02 EP claimed
US-5141999-A PREPARATION OF ANHYDRIDE-CAPPED POLYPHENYLENE ETHER IN A MELT PROCESS GENERAL ELECTRIC COMPANY (US) 1992-08-25 US claimed
US-5140077-A Copolymers of an acetyl or phenyl 4-aminosalicylic acid trimellitamide-end capped polyphenylene ether and a polyamide as compatilizers for polyether/amide blends; heat and oxidation resistance GENERAL ELECTRIC COMPANY (US) 1992-08-18 US claimed
JP-5066221-A None JP disclosed
EP-0148752-A2 Protease inhibitors G.D. Searle & Co. (US) 1985-07-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040072798-A1 Compositions comprising cyclodextrins and no-releasing drugs NOS1, NOS2, NOS3 CFD 694/4885KDM4E 4029/4885ALDH1A1 1731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.