Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.53 |
| ▸ | HTR1D | P28221 | 8/20 | 0.53 |
| ▸ | HTR1B | P28222 | 8/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 3/20 | 0.53 |
| ▸ | RBP4 | P02753 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705983 | 0.89 | MAPT (0.57) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL8700902 | 0.88 | CXCR3 (0.48) | RBP4THRBFAAHSMN1; SMN2MAPT | |
| SCHEMBL8705057 | 0.88 | HTR1A (0.52) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL8703773 | 0.88 | RBP4 (0.51) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL8700393 | 0.86 | RBP4 (0.58) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL6961576 | 0.85 | HTR1A (0.55) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL8705064 | 0.84 | HTR1A (0.52) | HTR1AHTR1DHTR1BRBP4THRB | |
| SCHEMBL8704931 | 0.84 | RBP4 (0.57) | HTR1AHTR1DHTR1BRBP4FAAH | |
| SCHEMBL9057833 | 0.84 | RBP4 (0.50) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| SCHEMBL8699470 | 0.83 | KMT2A (0.51) | HTR1AHTR1DHTR1BRBP4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |