Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652409 | 0.90 | KMT2A (0.48) | CXCR3KCNH2MAPTKMT2AMEN1 | |
| SCHEMBL9057833 | 0.90 | RBP4 (0.50) | RBP4FAAHSMN1; SMN2MAPTRAB9A | |
| SCHEMBL8702290 | 0.89 | RBP4 (0.48) | RBP4FAAHSMN1; SMN2MAPTRAB9A | |
| SCHEMBL8705064 | 0.89 | HTR1A (0.52) | RBP4SMN1; SMN2HTTMAPTRAB9A | |
| SCHEMBL8699566 | 0.88 | HTR1A (0.53) | RBP4FAAHSMN1; SMN2HTTMAPT | |
| SCHEMBL8705983 | 0.88 | MAPT (0.57) | RBP4SMN1; SMN2MAPTRAB9ATRPV1 | |
| SCHEMBL8699470 | 0.88 | KMT2A (0.51) | RBP4SMN1; SMN2MAPTRAB9ATRPV1 | |
| SCHEMBL8700940 | 0.88 | RBP4 (0.61) | RBP4HTTMAPTRAB9ATRPV1 | |
| SCHEMBL8703773 | 0.87 | RBP4 (0.51) | RBP4FAAHSMN1; SMN2HTTMAPT | |
| SCHEMBL8704636 | 0.87 | KMT2A (0.57) | RBP4SMN1; SMN2MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |