Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701671 | 0.87 | ADRA2A (0.42) | MEN1KMT2ASIGMAR1SLC18A2 | |
| SCHEMBL8699391 | 0.84 | SLC18A2 (0.41) | SLC18A2 | |
| SCHEMBL8699125 | 0.84 | ESR1 (0.42) | ALDH1A1NPSR1HSD17B10MEN1KMT2A | |
| SCHEMBL8701038 | 0.80 | NPC1 (0.54) | ALDH1A1NPSR1OPRD1MEN1NPC1 | |
| SCHEMBL8541698 | 0.80 | HRH3 (0.54) | SIGMAR1 | |
| SCHEMBL8695270 | 0.79 | ADRA2A (0.45) | ALDH1A1NPSR1HSD17B10OPRD1MEN1 | |
| SCHEMBL8699170 | 0.77 | SIGMAR1 (0.40) | ALDH1A1NPSR1HSD17B10OPRD1MEN1 | |
| SCHEMBL8699585 | 0.76 | SIGMAR1 (0.38) | ALDH1A1NPSR1HSD17B10SIGMAR1 | |
| SCHEMBL8542041 | 0.76 | CYP19A1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL8698587 | 0.75 | TBXAS1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |