Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653315 | 0.90 | PHGDH (0.62) | KMT2AATMMEN1PHGDHALDH1A1 | |
| SCHEMBL6953207 | 0.82 | LMNA (0.52) | KMT2AMEN1PHGDHALDH1A1CYP1A2 | |
| SCHEMBL9016346 | 0.82 | KMT2A (0.53) | KMT2AMEN1PHGDHALDH1A1CYP1A2 | |
| SCHEMBL6651537 | 0.82 | CYP3A4 (0.61) | KMT2AMEN1PHGDHALDH1A1CYP3A4 | |
| SCHEMBL6654161 | 0.82 | PHGDH (0.60) | KMT2AMEN1PHGDHALDH1A1CYP1A2 | |
| SCHEMBL27556985 | 0.81 | MEN1 (0.63) | KMT2AMEN1PHGDHALDH1A1CYP1A2 | |
| SCHEMBL6657881 | 0.81 | PHGDH (0.56) | KMT2AMEN1PHGDHALDH1A1CYP3A4 | |
| SCHEMBL6653829 | 0.80 | KMT2A (0.55) | KMT2AATMMEN1PHGDHALDH1A1 | |
| SCHEMBL8699629 | 0.80 | KDM4E (0.57) | KMT2AMEN1PHGDHALDH1A1CYP1A2 | |
| SCHEMBL6652129 | 0.80 | PHGDH (0.50) | KMT2AMEN1PHGDHALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |