Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653315 | 0.88 | PHGDH (0.62) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL27556985 | 0.84 | MEN1 (0.63) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL6953207 | 0.83 | LMNA (0.52) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL6654161 | 0.83 | PHGDH (0.60) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL6651537 | 0.83 | CYP3A4 (0.61) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL8699629 | 0.82 | KDM4E (0.57) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL6652129 | 0.82 | PHGDH (0.50) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL8699733 | 0.82 | KMT2A (0.52) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL6657881 | 0.81 | PHGDH (0.56) | KMT2AMEN1ALDH1A1PHGDHLMNA | |
| SCHEMBL27541031 | 0.81 | CYP3A4 (0.52) | KMT2AMEN1ALDH1A1PHGDHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |