Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701740 | 0.83 | IDO1 (0.38) | PPARAPPARGGGPS1IDO1AGXT | |
| SCHEMBL8715771 | 0.79 | IDO1 (0.39) | PPARAPPARGIDO1AGXT | |
| SCHEMBL8699744 | 0.77 | BTN3A1 (0.36) | PPARAPPARGGGPS1IDO1AGXT | |
| SCHEMBL8698655 | 0.76 | IDO1 (0.39) | PPARAPPARGIDO1AGXT | |
| SCHEMBL8699737 | 0.76 | GGPS1 (0.39) | GGPS1IDO1AGXT | |
| SCHEMBL15155730 | 0.75 | PPARG (0.47) | PPARAPPARG | |
| SCHEMBL15778630 | 0.74 | IDO1 (0.60) | IDO1AGXT | |
| SCHEMBL8699358 | 0.74 | IDO1 (0.39) | IDO1AGXT | |
| SCHEMBL8704540 | 0.73 | IDO1 (0.33) | PPARAPPARGIDO1AGXT | |
| SCHEMBL8702327 | 0.73 | PPARA (0.61) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008838-A1 | SUBSTITUTED AMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |