Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | AGXT | P21549 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701740 | 0.83 | IDO1 (0.38) | BTN3A1PPARGPPARAIDO1AGXT | |
| SCHEMBL8715771 | 0.79 | IDO1 (0.39) | BTN3A1PPARGPPARAIDO1AGXT | |
| SCHEMBL8699741 | 0.77 | PPARA (0.43) | PPARGPPARAIDO1AGXTGGPS1 | |
| SCHEMBL8698655 | 0.76 | IDO1 (0.39) | BTN3A1PPARGPPARAIDO1AGXT | |
| SCHEMBL8702327 | 0.75 | PPARA (0.61) | PPARGPPARACYP4F2CYP4A11MAOB | |
| SCHEMBL8703174 | 0.75 | MAPK1 (0.41) | — | |
| SCHEMBL15778630 | 0.74 | IDO1 (0.60) | IDO1AGXTMAOB | |
| SCHEMBL8699737 | 0.74 | GGPS1 (0.39) | IDO1AGXTGGPS1 | |
| SCHEMBL8699358 | 0.74 | IDO1 (0.39) | IDO1AGXTCYP4F2CYP4A11MAOB | |
| SCHEMBL9665663 | 0.73 | PPARA (0.37) | BTN3A1PPARGPPARAIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008838-A1 | SUBSTITUTED AMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |