Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.50 |
| ▸ | GOT1 | P17174 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697752 | 0.86 | GOT1 (0.53) | CDK4GOT1MAPTALDH1A1KDM4E | |
| SCHEMBL8698886 | 0.85 | CDK4 (0.56) | CDK4MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8697249 | 0.84 | GOT1 (0.60) | CDK4GOT1MAPTALDH1A1MEN1 | |
| SCHEMBL8697853 | 0.81 | CDK4 (0.63) | CDK4MAPTALDH1A1HTR1AADRA2A | |
| SCHEMBL8697962 | 0.75 | CDK4 (0.53) | CDK4MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8998960 | 0.71 | CDK4 (0.71) | CDK4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30579374 | 0.71 | CDK4 (0.71) | CDK4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8701530 | 0.70 | CDK4 (0.48) | CDK4MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8695756 | 0.70 | CDK4 (0.45) | CDK4MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9854721 | 0.67 | CDK4 (0.65) | CDK4MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |