Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697752 | 0.90 | GOT1 (0.53) | GOT1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8699800 | 0.84 | CDK4 (0.50) | GOT1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8698886 | 0.82 | CDK4 (0.56) | MAPTALDH1A1MEN1KMT2ACDK4 | |
| SCHEMBL8697853 | 0.78 | CDK4 (0.63) | MAPTALDH1A1CDK4SMN1; SMN2CCND1 | |
| SCHEMBL8697962 | 0.72 | CDK4 (0.53) | MAPTALDH1A1MEN1KMT2ACDK4 | |
| SCHEMBL8695756 | 0.69 | CDK4 (0.45) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8699518 | 0.69 | ALDH1A1 (0.44) | MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30579374 | 0.69 | CDK4 (0.71) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8998960 | 0.69 | CDK4 (0.71) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8701009 | 0.68 | ALOX5 (0.46) | MAPTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |