Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 4/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697962 | 0.82 | CDK4 (0.53) | CDK4GAAALDH1A1MC5RCCND1 | |
| SCHEMBL8698309 | 0.82 | MLYCD (0.47) | GAALMNAKDM4EMEN1KMT2A | |
| SCHEMBL8701794 | 0.82 | KMT2A (0.52) | CDK4GAALMNAALDH1A1CCND1 | |
| SCHEMBL8697853 | 0.81 | CDK4 (0.63) | CDK4GAAALDH1A1MC5RCCND1 | |
| SCHEMBL8695080 | 0.79 | MLYCD (0.41) | LMNAALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL8695261 | 0.78 | ALOX5 (0.45) | GAALMNAALDH1A1KDM4E | |
| SCHEMBL8792800 | 0.78 | CDK4 (0.43) | CDK4GAALMNAALDH1A1MC5R | |
| SCHEMBL8698886 | 0.75 | CDK4 (0.56) | CDK4GAAALDH1A1MC5RCCND1 | |
| SCHEMBL8698422 | 0.74 | MLYCD (0.35) | LMNAALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL8695756 | 0.73 | CDK4 (0.45) | CDK4LMNAALDH1A1CCND1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |