Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 4/20 | 0.49 |
| ▸ | MC5R | P33032 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697249 | 0.90 | GOT1 (0.60) | GOT1CDK4MAPTALDH1A1CCND1 | |
| SCHEMBL8699800 | 0.86 | CDK4 (0.50) | GOT1CDK4MC5RMAPTALDH1A1 | |
| SCHEMBL8698886 | 0.85 | CDK4 (0.56) | CDK4MC5RMAPTALDH1A1CCND1 | |
| SCHEMBL8697853 | 0.80 | CDK4 (0.63) | CDK4MC5RMAPTALDH1A1CCND1 | |
| SCHEMBL8699518 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1RAB9AKMT2AGAA | |
| SCHEMBL8701009 | 0.78 | ALOX5 (0.46) | MAPTALDH1A1RAB9AKMT2AMAPK1 | |
| SCHEMBL8695688 | 0.74 | NOX1 (0.36) | ALDH1A1NPSR1MAOA | |
| SCHEMBL8697962 | 0.74 | CDK4 (0.53) | CDK4MC5RMAPTALDH1A1CCND1 | |
| SCHEMBL8998960 | 0.70 | CDK4 (0.71) | CDK4MC5RMAPTALDH1A1CCND1 | |
| SCHEMBL30579374 | 0.70 | CDK4 (0.71) | CDK4MC5RMAPTALDH1A1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | claimed |
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |