Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706207 | 0.85 | FGFR1 (0.53) | ALDH1A1FGFR1MEN1KMT2AMAPT | |
| SCHEMBL8446574 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL8700037 | 0.84 | FGFR1 (0.49) | ALDH1A1HTTFGFR1MAPTRAB9A | |
| SCHEMBL8707037 | 0.84 | FGFR1 (0.49) | ALDH1A1HTTFGFR1MEN1KMT2A | |
| SCHEMBL8706450 | 0.84 | FGFR1 (0.55) | ALDH1A1FGFR1MEN1KMT2AMAPT | |
| SCHEMBL8707738 | 0.81 | FGFR1 (0.47) | ALDH1A1HTTFGFR1MEN1KMT2A | |
| SCHEMBL8706542 | 0.81 | FGFR1 (0.47) | ALDH1A1HTTFGFR1MAPTRAB9A | |
| SCHEMBL8703728 | 0.81 | FGFR1 (0.47) | ALDH1A1FGFR1MAPTRAB9AGAA | |
| SCHEMBL8705277 | 0.81 | FGFR1 (0.47) | ALDH1A1FGFR1MAPTRAB9AGAA | |
| SCHEMBL8706115 | 0.81 | FGFR1 (0.47) | ALDH1A1FGFR1MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |