Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 4/20 | 0.39 |
| ▸ | NEK2 | P51955 | 2/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707037 | 0.87 | FGFR1 (0.49) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8706207 | 0.85 | FGFR1 (0.53) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8700037 | 0.85 | FGFR1 (0.49) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8706450 | 0.85 | FGFR1 (0.55) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8706542 | 0.84 | FGFR1 (0.47) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8706115 | 0.84 | FGFR1 (0.47) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8444311 | 0.83 | SLC9A1 (0.44) | — | |
| SCHEMBL8707738 | 0.82 | FGFR1 (0.47) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8703728 | 0.82 | FGFR1 (0.47) | FGFR1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL8699860 | 0.81 | ALDH1A1 (0.52) | FGFR1ALDH1A1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |