Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706207 | 0.88 | FGFR1 (0.53) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8707037 | 0.87 | FGFR1 (0.49) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8706450 | 0.87 | FGFR1 (0.55) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8707738 | 0.85 | FGFR1 (0.47) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8705277 | 0.85 | FGFR1 (0.47) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8706542 | 0.85 | FGFR1 (0.47) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8703728 | 0.85 | FGFR1 (0.47) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8706115 | 0.85 | FGFR1 (0.47) | FGFR1MAPTRAB9ASRCNEK2 | |
| SCHEMBL8699860 | 0.84 | ALDH1A1 (0.52) | FGFR1MAPTRAB9ASRCALDH1A1 | |
| SCHEMBL8447166 | 0.83 | SLC9A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |