Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | AOC2 | O75106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815462 | 0.83 | PTGER1 (0.54) | CYP2C9PTGER1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL7829416 | 0.82 | RAB9A (0.50) | CYP2C9PTGER1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL7824012 | 0.81 | F10 (0.44) | F10F2CYP2C9PTGER1KMT2A | |
| SCHEMBL8700313 | 0.81 | AOC2 (0.43) | F10F2KMT2ATDP1PRSS1 | |
| Hydrochloric Acid SCHEMBL8699397 | 0.80 | AOC2 (0.43) | F10F2KMT2ATDP1PRSS1 | |
| SCHEMBL8699862 | 0.79 | AOC2 (0.42) | F10F2KMT2ATDP1PRSS1 | |
| Hydrochloric Acid SCHEMBL8701063 | 0.78 | AOC2 (0.41) | F10F2KMT2ATDP1PRSS1 | |
| SCHEMBL29008250 | 0.76 | LMNA (0.45) | KMT2ASLC6A2SLC6A3TDP1RAB9A | |
| SCHEMBL17894403 | 0.75 | SMPD1 (0.69) | F10F2KMT2ARAB9ASMPD1 | |
| Hydrochloric Acid SCHEMBL8705820 | 0.74 | AOC2 (0.42) | F10F2KMT2ATDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |