Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.43 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.43 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 7/20 | 0.39 |
| ▸ | HTR7 | P34969 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707718 | 0.94 | SLC9A1 (0.49) | SLC9A1SLC9A3SLC9A2HTR2BHTR7 | |
| SCHEMBL7824958 | 0.84 | SLC9A1 (0.53) | SLC9A1SLC9A3SLC9A2HTR2BHTR7 | |
| SCHEMBL7822660 | 0.80 | SLC9A1 (0.59) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL27401335 | 0.80 | SLC9A1 (0.59) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8707632 | 0.76 | ALDH1A1 (0.66) | ALDH1A1CYP2C19CYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL8703973 | 0.75 | AOC2 (0.39) | SLC9A1SLC9A3SLC9A2HTR2BHTR7 | |
| SCHEMBL7825554 | 0.75 | SLC9A1 (0.55) | SLC9A1SLC9A3SLC9A2HTR2BHTR7 | |
| Hydrochloric Acid SCHEMBL7825501 | 0.74 | SLC9A1 (0.54) | SLC9A1SLC9A3SLC9A2HTR2BHTR7 | |
| SCHEMBL8703469 | 0.73 | LMNA (0.40) | SLC9A1SLC9A3SLC9A2ALDH1A1CYP2C19 | |
| SCHEMBL1388036 | 0.73 | HTR2B (0.46) | SLC9A1SLC9A3SLC9A2HTR2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |