Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | AOC2 | O75106 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8701395 | 0.84 | HPGD (0.53) | ALDH1A1HPGDKMT2AMEN1CYP1A2 | |
| SCHEMBL8699333 | 0.80 | AOC2 (0.47) | ALDH1A1HPGDKMT2AMEN1L3MBTL1 | |
| SCHEMBL7823729 | 0.79 | SLC9A1 (0.43) | ALDH1A1GRM5CYP2D6CYP2C19 | |
| SCHEMBL7829966 | 0.79 | RBP4 (0.43) | ALDH1A1GRM5HPGDKMT2AMEN1 | |
| SCHEMBL8704334 | 0.78 | AOC2 (0.43) | ALDH1A1HPGDCYP1A2L3MBTL1AOC2 | |
| Hydrochloric Acid SCHEMBL8707259 | 0.75 | AOC2 (0.41) | ALDH1A1KMT2AMEN1L3MBTL1AOC2 | |
| SCHEMBL8183727 | 0.75 | AOC2 (0.43) | L3MBTL1AOC2CASP6MAPTRAB9A | |
| SCHEMBL8699717 | 0.74 | AOC2 (0.40) | ALDH1A1KMT2AMEN1L3MBTL1AOC2 | |
| Hydrochloric Acid SCHEMBL8704455 | 0.74 | AOC2 (0.42) | L3MBTL1AOC2CASP6MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8704321 | 0.74 | AOC2 (0.42) | ALDH1A1KMT2AMEN1L3MBTL1AOC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |