Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410013 | 0.72 | KDM4E (0.60) | MTNR1AMTNR1BKDM4ELMNAPOLB | |
| SCHEMBL10615237 | 0.67 | MTNR1B (0.42) | MTNR1AMTNR1B | |
| SCHEMBL6635759 | 0.67 | MEN1 (0.56) | MTNR1AMTNR1BKDM4EMAPT | |
| SCHEMBL6635718 | 0.65 | MEN1 (0.50) | MTNR1AMTNR1BKDM4EMAPT | |
| SCHEMBL18071522 | 0.63 | ACHE (0.49) | KDM4ELMNAPOLBMAPT | |
| SCHEMBL6633100 | 0.63 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6633475 | 0.63 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6633479 | 0.63 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL6633781 | 0.63 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL8410015 | 0.62 | MTNR1A (0.62) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712312-A | MELATONINERGIC RECEPTOR LIGANDS, TREATMENT OF SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |