Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | AOC2 | O75106 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8703965 | 0.99 | SPHK1 (0.38) | PLK1SPHK2SPHK1AOC2SCN5A | |
| SCHEMBL8699878 | 0.84 | AOC2 (0.40) | AOC2SMN1; SMN2ALDH1A1PLAULMNA | |
| SCHEMBL8699298 | 0.81 | NQO2 (0.46) | PLK1AOC2SMN1; SMN2ALDH1A1PLAU | |
| SCHEMBL8707021 | 0.81 | AOC2 (0.36) | AOC2SMN1; SMN2ALDH1A1PLAULMNA | |
| SCHEMBL8703342 | 0.81 | EGFR (0.33) | PLK1SPHK2SPHK1SCN5ASCN2A | |
| Hydrochloric Acid SCHEMBL8703778 | 0.80 | SPHK1 (0.33) | PLK1SPHK2SPHK1SCN5ASCN2A | |
| SCHEMBL7825760 | 0.79 | KDM5A (0.45) | ALDH1A1LMNA | |
| SCHEMBL8703469 | 0.79 | LMNA (0.40) | AOC2SMN1; SMN2ALDH1A1PLAULMNA | |
| SCHEMBL1388128 | 0.79 | SLC9A1 (0.43) | — | |
| SCHEMBL8705215 | 0.78 | NQO2 (0.45) | AOC2SMN1; SMN2ALDH1A1PLAUCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | claimed |
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |