Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30612735 | 0.69 | ALDH1A1 (0.55) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL5913910 | 0.69 | ALDH1A1 (0.55) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL2400816 | 0.69 | KDM4E (0.49) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL2126375 | 0.68 | ALDH1A1 (0.54) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL1387824 | 0.68 | NPC1 (0.35) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL30284405 | 0.67 | KDM4E (0.50) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL12588590 | 0.67 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL361847 | 0.67 | KDM4E (0.50) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8681103 | 0.67 | KDM4E (0.50) | HTTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL22801902 | 0.67 | KDM4E (0.47) | HTTSMN1; SMN2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705102-A | Photochromic spironaphthopyran compounds | VISION-EASE LENS, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| US-5628935-A | Photochromic spironaphthopyran compounds | VISION-EASE LENS, INC. (US) | 1997-05-13 | — | — | US | disclosed |