SCHEMBL8700276

SCHEMBL8700276

C1CC23CC4CC(CC(C4)[C]12)C3

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.34
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.32
GRIN2D O15399 2/20 0.32
GRIN3B O60391 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN2C Q14957 2/20 0.32
GRIN3A Q8TCU5 2/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
GFER P55789 1/20 0.31
KMT2A Q03164 1/20 0.31
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SLC22A2 O15244 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19747326 0.66 LMNA (0.41) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL21378836 0.64 SMN1; SMN2 (0.33) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL21378835 0.62 HSD11B1 (0.40) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL10529647 0.60 HSD11B1 (0.43) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL6400549 0.60 HSD11B1 (0.43) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL28889763 0.59 ALDH1A1 (0.40) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL2763437 0.58 LMNA (0.77) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL28299622 0.57 LMNA (0.43) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL548854 0.57 POLB (0.43) LMNAALDH1A1SMN1; SMN2GRIN2DGRIN3B
SCHEMBL7709513 0.56 LMNA (0.63) LMNAALDH1A1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5851727-A Photosensitive polymers and photoresist compositions containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 1998-12-22 US claimed
US-5851727-A Photosensitive polymers and photoresist compositions containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 1998-12-22 US disclosed