SCHEMBL8700447

SCHEMBL8700447

CCC(CN(C)C)C(=O)c1ccccc1OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
CTSD P07339 1/20 0.46
NPC1 O15118 5/20 0.44
RAB9A P51151 4/20 0.44
HTT P42858 2/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
ATM Q13315 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 3/20 0.41
TP53 P04637 2/20 0.41
GLA P06280 1/20 0.41
LMNA P02545 1/20 0.41
STAT3 P40763 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
TSHR P16473 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7124014 0.85 HPGD (0.48) ALDH1A1CTSDNPC1RAB9AHTT
SCHEMBL7124018 0.85 HPGD (0.48) ALDH1A1CTSDNPC1RAB9AHTT
Hydrochloric Acid SCHEMBL7164809 0.83 TP53 (0.47) CTSDNPC1RAB9AHTTMAPT
Hydrochloric Acid SCHEMBL7164811 0.83 TP53 (0.47) CTSDNPC1RAB9AHTTMAPT
SCHEMBL18334685 0.82 CTSD (0.49) ALDH1A1CTSDNPC1RAB9AHTT
SCHEMBL8701928 0.79 RAB9A (0.46) ALDH1A1NPC1RAB9AHTTMAPT
Iodide SCHEMBL8700644 0.78 CTSD (0.45) ALDH1A1CTSDNPC1RAB9AHTT
SCHEMBL8698015 0.77 KMT2A (0.50) ALDH1A1NPC1RAB9AHTTMAPT
SCHEMBL17114455 0.76 CTSD (0.53) ALDH1A1CTSDNPC1RAB9AHTT
SCHEMBL13003559 0.76 CTSD (0.53) ALDH1A1CTSDNPC1RAB9AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998003479-A1 NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1998-01-29 WO disclosed