Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125382 | 0.84 | RAB9A (0.47) | RAB9ANPC1MAPTHTTATM | |
| SCHEMBL7125378 | 0.84 | RAB9A (0.47) | RAB9ANPC1MAPTHTTATM | |
| SCHEMBL8702071 | 0.83 | CES2 (0.45) | RAB9ANPC1MAPTHTTATM | |
| Hydrochloric Acid SCHEMBL7164488 | 0.82 | MAPT (0.49) | RAB9ANPC1MAPTHTTATM | |
| Hydrochloric Acid SCHEMBL7165976 | 0.82 | MAPT (0.49) | RAB9ANPC1MAPTHTTATM | |
| SCHEMBL8702566 | 0.81 | CES2 (0.47) | RAB9ANPC1MAPTHTTATM | |
| SCHEMBL8700447 | 0.79 | ALDH1A1 (0.49) | RAB9ANPC1MAPTHTTATM | |
| SCHEMBL8698015 | 0.79 | KMT2A (0.50) | RAB9ANPC1MAPTHTTATM | |
| SCHEMBL28032692 | 0.78 | CES2 (0.47) | RAB9ANPC1MAPTCES2CES1 | |
| Iodide SCHEMBL8697992 | 0.77 | CES2 (0.44) | RAB9ANPC1MAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998003478-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |