Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18334708 | 0.82 | MEN1 (0.42) | HPGDALDH1A1NPC1L3MBTL1LMNA | |
| SCHEMBL29018644 | 0.82 | CTSD (0.53) | CTSDHPGDALDH1A1NPC1XBP1 | |
| SCHEMBL13003559 | 0.82 | CTSD (0.53) | CTSDHPGDALDH1A1NPC1XBP1 | |
| SCHEMBL8700447 | 0.82 | ALDH1A1 (0.49) | CTSDHPGDALDH1A1NPC1TP53 | |
| SCHEMBL11438001 | 0.81 | SGMS2 (0.50) | ALDH1A1NPC1L3MBTL1LMNAKMT2A | |
| SCHEMBL31257134 | 0.81 | CTSD (0.55) | CTSDHPGDALDH1A1NPC1XBP1 | |
| SCHEMBL2145919 | 0.80 | CTSD (0.41) | CTSDHPGDALDH1A1NPC1XBP1 | |
| SCHEMBL2145916 | 0.80 | CTSD (0.41) | CTSDHPGDALDH1A1NPC1XBP1 | |
| SCHEMBL3081274 | 0.80 | CTSD (0.41) | CTSDHPGDALDH1A1NPC1XBP1 | |
| SCHEMBL2145924 | 0.80 | CTSD (0.41) | CTSDHPGDALDH1A1NPC1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107787321-B | Novel5-HT2Antagonists | 安娜玛有限公司 | 2021-10-01 | — | — | CN | disclosed |
| EP-3310762-B1 | NOVEL 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2020-08-05 | — | — | EP | disclosed |
| US-10544103-B2 | 5-HT2 antagonists | ANAMAR AB (SE) | 2020-01-28 | — | — | US | disclosed |
| US-20180155292-A1 | NOVEL 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2018-06-07 | — | — | US | disclosed |
| EP-3310762-A1 | NOVEL 5-HT2 ANTAGONISTS | Anamar AB (SE) | 2018-04-25 | — | — | EP | disclosed |
| WO-2016207231-A1 | NOVEL 5-HT2 ANTAGONISTS | ANAMAR AB (SE) | 2016-12-29 | — | — | WO | disclosed |
| EP-3109237-A1 | NOVEL 5-HT2 ANTAGONISTS | AnaMar AB (SE) | 2016-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544103-B2 | 5-HT2 antagonists | HTR2B, HTR2C, HTR2A | CTSD 3804/4885HPGD 1641/4885ALDH1A1 2604/4885 |
| US-20180155292-A1 | NOVEL 5-HT2 ANTAGONISTS | HTR2B, TPH2, HTR2C | CTSD 3984/4885HPGD 1021/4885ALDH1A1 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.