Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700375 | 0.91 | SLC9A1 (0.38) | SLC9A1SLC9A3SLC9A2KMT2ACDK1 | |
| SCHEMBL8702119 | 0.89 | SLC9A1 (0.46) | SLC9A1SLC9A3SLC9A2KMT2ACDK1 | |
| SCHEMBL8700976 | 0.87 | KMT2A (0.37) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 | |
| SCHEMBL8703757 | 0.84 | PKM (0.40) | SLC9A1SLC9A3SLC9A2KMT2ACDK1 | |
| SCHEMBL8700586 | 0.83 | SLC9A1 (0.50) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 | |
| SCHEMBL8704148 | 0.82 | EED (0.40) | SLC9A1SLC9A3SLC9A2KMT2AKDM4E | |
| SCHEMBL8703472 | 0.82 | KDM4E (0.41) | SLC9A1SLC9A3SLC9A2KMT2ACA2 | |
| SCHEMBL8703455 | 0.82 | MAPT (0.41) | SLC9A1SLC9A3SLC9A2KMT2AHSD17B10 | |
| SCHEMBL8705327 | 0.82 | HTT (0.41) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8699798 | 0.81 | CFTR (0.39) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |