Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | SDHB | P21912 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703757 | 0.84 | PKM (0.40) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 | |
| SCHEMBL8700586 | 0.83 | SLC9A1 (0.50) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 | |
| SCHEMBL8704148 | 0.82 | EED (0.40) | SLC9A1SLC9A3SLC9A2KMT2A | |
| SCHEMBL8703455 | 0.82 | MAPT (0.41) | SLC9A1SLC9A3SLC9A2KMT2A | |
| SCHEMBL8703472 | 0.82 | KDM4E (0.41) | CFTRSLC9A1SLC9A3SLC9A2KMT2A | |
| SCHEMBL8700122 | 0.82 | ALDH1A1 (0.42) | CFTRSDHBKMT2ANR1H2NR1H3 | |
| SCHEMBL8700491 | 0.81 | SLC9A1 (0.37) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 | |
| SCHEMBL8702221 | 0.81 | SLC9A1 (0.37) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 | |
| SCHEMBL8700375 | 0.81 | SLC9A1 (0.38) | SLC9A1SLC9A3SLC9A2KMT2AVCAM1 | |
| SCHEMBL8447969 | 0.81 | SLC9A1 (0.57) | SLC9A1SLC9A3SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |