Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707029 | 0.91 | AOC2 (0.39) | AOC2POLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8300855 | 0.90 | AOC2 (0.43) | AOC2POLBSMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8702987 | 0.89 | AOC2 (0.43) | AOC2POLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7816169 | 0.80 | SLC9A1 (0.36) | AOC2VHLELOCELOB | |
| SCHEMBL8699333 | 0.78 | AOC2 (0.47) | AOC2POLBSMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8704665 | 0.77 | AOC2 (0.41) | AOC2POLBSMN1; SMN2ALDH1A1LMNA | |
| Guanidine SCHEMBL8700560 | 0.76 | AOC2 (0.33) | AOC2VHLELOCELOB | |
| Hydrochloric Acid SCHEMBL8706003 | 0.75 | AOC2 (0.39) | AOC2POLBSMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8704074 | 0.75 | SMN1; SMN2 (0.40) | AOC2POLBSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL8701427 | 0.74 | AOC2 (0.40) | AOC2LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |