Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697707 | 0.80 | TXNRD1 (0.48) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8693826 | 0.76 | SMN1; SMN2 (0.46) | MEN1KMT2AALDH1A1RAB9AHPGD | |
| SCHEMBL6593403 | 0.75 | MAPT (0.56) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8694999 | 0.75 | ALDH1A1 (0.39) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL1446429 | 0.73 | MAPT (0.57) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL998698 | 0.73 | HPD (0.42) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL999603 | 0.73 | HPD (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL3327817 | 0.72 | MAPT (0.56) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL15918696 | 0.72 | MAPT (0.60) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL998546 | 0.70 | HPD (0.39) | MAPTMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801120-A | HERBICIDES FOR CONTROLLING WEEDS | SANDOZ LTD. (CH) | 1998-09-01 | — | — | US | disclosed |
| US-5700762-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-12-23 | — | — | US | disclosed |
| US-5608101-A | HERBICIDES | NOVARTIS AG (CH) | 1997-03-04 | — | — | US | disclosed |
| EP-0338992-A2 | Substituted aryl and heteroaryl bicyclodiones | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |