Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.48 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.48 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HPD | P32754 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700816 | 0.80 | MAPT (0.43) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL29901773 | 0.77 | TXNRD1 (0.64) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL8698297 | 0.76 | TXNRD1 (0.43) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL29901717 | 0.71 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL8693826 | 0.68 | SMN1; SMN2 (0.46) | KMT2AMEN1RAB9AHPDSMN1; SMN2 | |
| SCHEMBL998698 | 0.68 | HPD (0.42) | KMT2AMEN1RAB9ACDK2MAPT | |
| SCHEMBL8695352 | 0.68 | PKM (0.36) | KMT2APOLBL3MBTL1LMNAHTT | |
| SCHEMBL999603 | 0.66 | HPD (0.42) | KMT2AMEN1RAB9AGAAMAPT | |
| SCHEMBL5234315 | 0.66 | TXNRD1 (0.64) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 | |
| SCHEMBL10277715 | 0.66 | TXNRD1 (0.47) | TXNRD1TXNRD3TXNRD2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801120-A | HERBICIDES FOR CONTROLLING WEEDS | SANDOZ LTD. (CH) | 1998-09-01 | — | — | US | disclosed |
| US-5700762-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-12-23 | — | — | US | disclosed |
| US-5608101-A | HERBICIDES | NOVARTIS AG (CH) | 1997-03-04 | — | — | US | disclosed |
| EP-0338992-A2 | Substituted aryl and heteroaryl bicyclodiones | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |