Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777177 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SPRSIGMAR1CNR2CHRM1 | |
| SCHEMBL8695503 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SPRSIGMAR1CNR2CHRM1 | |
| SCHEMBL1365607 | 0.85 | HSD11B1 (0.48) | SIGMAR1CNR2CHRM1CHRM2CHRM4 | |
| SCHEMBL928364 | 0.85 | HSD11B1 (0.48) | SIGMAR1CNR2CHRM1CHRM2CHRM4 | |
| SCHEMBL8013274 | 0.85 | HSD11B1 (0.48) | SIGMAR1CNR2CHRM1CHRM2CHRM4 | |
| SCHEMBL18112122 | 0.85 | HSD11B1 (0.48) | SIGMAR1CNR2CHRM1CHRM2CHRM4 | |
| SCHEMBL5857322 | 0.84 | TSHR (0.49) | ALDH1A1SIGMAR1CHRM1CHRM2CHRM4 | |
| SCHEMBL12356590 | 0.83 | LTA4H (0.53) | SPRSIGMAR1CNR2CHRM1CHRM2 | |
| SCHEMBL18711752 | 0.83 | LTA4H (0.53) | SPRSIGMAR1CNR2CHRM1CHRM2 | |
| SCHEMBL5041382 | 0.83 | SIGMAR1 (0.47) | SPRSIGMAR1CNR2CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849734-A | Muscarinic receptor ligands | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1998-12-15 | — | — | US | disclosed |
| US-5674877-A | TREATMENT OF PSYCHOLOGICAL DISORDERS, SCHIZOPHRENIA | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-10-07 | — | — | US | disclosed |
| US-5561127-A | TREATING ANXIETY, SCHIZOPHRENIA | ALLELIX BIOPHARMACEUTICALS, INC. (CA) | 1996-10-01 | — | — | US | disclosed |