Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701376 | 0.91 | RBP4 (0.48) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL6961499 | 0.90 | MAPT (0.48) | THRBMAPTLMNAALDH1A1TSHR | |
| SCHEMBL8702748 | 0.90 | RBP4 (0.45) | THRBMAPTLMNAALDH1A1TSHR | |
| SCHEMBL8703704 | 0.90 | RBP4 (0.52) | THRBMAPTALDH1A1MAPK1KMT2A | |
| SCHEMBL8705064 | 0.88 | HTR1A (0.52) | THRBMAPTLMNAALDH1A1TSHR | |
| SCHEMBL8703304 | 0.87 | MAPT (0.55) | MAPTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL6960671 | 0.86 | KMT2A (0.47) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL8700061 | 0.85 | MAPT (0.57) | MAPTLMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL9057828 | 0.85 | MAPT (0.53) | MAPTLMNAALDH1A1MAPK1KMT2A | |
| SCHEMBL8700940 | 0.83 | RBP4 (0.61) | MAPTLMNAALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |