Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 14/20 | 0.36 |
| ▸ | HTR6 | P50406 | 14/20 | 0.36 |
| ▸ | HTR1A | P08908 | 12/20 | 0.36 |
| ▸ | DRD2 | P14416 | 12/20 | 0.36 |
| ▸ | HTR2A | P28223 | 12/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589168 | 0.83 | HTR7 (0.36) | HTR7HTR6HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL8716045 | 0.82 | HTR7 (0.35) | HTR7HTR6HTR1ADRD2HTR2A | |
| SCHEMBL8708955 | 0.82 | HTR2A (0.35) | HTR7HTR6HTR1ADRD2HTR2A | |
| SCHEMBL8713773 | 0.82 | ACHE (0.34) | HTR7HTR6HTR1ADRD2HTR2A | |
| SCHEMBL8718329 | 0.76 | ALDH1A1 (0.33) | HTR7HTR6HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7872294 | 0.75 | ALDH1A1 (0.33) | HTR7HTR6HTR1ADRD2HTR2A | |
| SCHEMBL8716559 | 0.75 | ALDH1A1 (0.35) | HTR7HTR6HTR1ADRD2HTR2A | |
| SCHEMBL7871633 | 0.74 | EPHX1 (0.35) | HTR7HTR6HTR1ADRD2HTR2A | |
| SCHEMBL8712584 | 0.73 | ALDH1A1 (0.32) | RORCCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL7863539 | 0.73 | EPHX1 (0.34) | HTR7HTR6HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998047901-A1 | PROCESS FOR PRODUCING TRICYCLIC COMPOUNDS AND THEIR INTERMEDIATES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |
| EP-0826686-A2 | Tricyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |